Cockroft–Gault or abbreviated-MDRD equations—which ‘weighs’ more in cardiovascular risk?

Milestones in cardiovascular medicine: 10 or more?

Abbreviated or not abbreviated? Is it the right question?

and cause of death among elderly chronic obstructive disease patients after first admission to hospital. Respiration 1997;64:281–4. 7 Zielinski J, MacNee W, Wedzicha J, et al. Causes of death in patients with COPD and chronic respiratory failure. Monaldi Arch Chest Dis 1997;52:43–7. 8 Hansell AL. Lies, damned lies and mortality statistics? Thorax 2006;61:923–4. 9 Sin DD, Man SFP. Cooling the fi...

Proteomics: The Nucleolus Weighs In

Numerous studies have indicated that the nucleolus is involved in a variety of cellular processes besides its well-known function in ribosome biosynthesis. A recent study describing the nucleolar proteome opens the way to new avenues of research on this important nuclear suborganelle.

Bone Weighs in on Obesity

Obesity, insulin resistance, and diabetes are related disorders of energy metabolism for which therapies are suboptimal. In this issue of Cell, Lee et al. (2007) demonstrate in mice that bone regulates the insulin/glucose axis and energy metabolism, providing a new framework for approaching common disorders of bioenergetics.

Cardiovascular Risk in Obesity what is more?The Omentin

Obesity increases the development of morbidity and mortality via varieties of severe cardiovascular diseases. Omentin is a newly identified adipokine selectively expressed in visceral adipose tissue. Clinical and experimental investigations suggested omentin as a critical mediator of cardiovascular homeostasis. Its ability to decrease insulin resistance in combination with its anti-atherogenic ...